Dopram (Doxapram): Uses, Dosage, Side Effects.
Doxapram is a respiratory stimulant with analeptic activity. Doxapram, independent of oxygen levels, directly stimulates the peripheral carotid chemoreceptors, possibly by inhibiting the potassium channels of type I cells within the carotid body, thereby stimulating catecholamines release. This results in the prevention or reversal of both narcotic- and CNS depressant-induced respiratory.
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Doxapram(Dopram) generic is a respiratory stimulant, prescribed for airway obstruction and drug induced respiratory depression. It alters neurotransmitters in the brain that stimulate breathing.
Doxapram: Indication, Dosage, Side Effect, Precaution.
This medication can be used to treat breathing problems due to overdose of certain drugs (e.g., narcotic analgesics, barbiturates), lung disease (chronic obstructive pulmonary disease) and in the recovery period after anesthesia. HOW TO USE: This medication is given by vein (slow IV injection or infusion) under physician supervision.
Dopram (doxapram) dosing, indications, interactions.
Doxapram acts as a ventilatory stimulant and Dopram Injection is used following anaesthesia to stimulate ventilation in the post-operative period as an aid to the reduction of post-operative pulmonary complications, and to permit the use of effective doses of narcotic analgesics without associated problems of ventilatory depression.
Doxapram injection doses and uses - Anesthesia General.
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Doxapram Intravenous: Uses, Side Effects, Interactions.
R07AB01 - doxapram; Belongs to the class of respiratory stimulants. Used in treatment of respiratory diseases.
The effects of doxapram on medullary respiratory neurones.
Doxapram acts by promoting excitation of central neurons. It produces respiratory stimulation by an action on peripheral carotid and aortic body chemoreceptors. As the dose is increased Doxapram stimulates respiratory centers in the medulla and other parts of brain. The respiratory stimulant action is manifested by an increase in tidal volume with a slight increase in respiratory rate.
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Dopram-V Dropper 10 ml - Grovet.com.
Dysrhythmias consisting of self-limiting or single ventricular extra beats were observed after doxapram was given by injection; it was suggested that electrocardiographic dysrhythmias occurring in anesthesia could be associated with analeptic drug administration (5 ). Doxapram is used to treat idiopathic apnea in premature infants.
Errors in prescribing, preparing, and giving medicines.
When doxapram is mixed with minocycline hydrochloride, there is a loss of 8% of doxapram in 3 hours and a 13% loss of doxapram in 6 hours. HOW SUPPLIED DOPRAM Injection (doxapram hydrochloride injection, USP) is available in boxes of six 20 mL multiple dose vials containing 20 mg of doxapram hydrochloride per mL with benzyl alcohol 0.9% as the preservative (NDC 0641-6018-06).
Caffeine: Uses, Side Effects, Interactions, Dosage, and.
Doxapram is a specific respiratory stimulant. It stimulates the respiratory center preferentially and has relatively less effect on cortical and spinal sites. Following intravenous doxapram injection the drug stimulates ventilation and increases cardiac output and work.
Canadian Thoracic Society recommendations for management.
Doxapram has the following interaction information: Aminophylline. Aminophylline increases the risk of agitation when given with doxapram. Manufacturer advises caution. Severity of interaction: Moderate Evidence for interaction: Study. Isocarboxazid. Isocarboxazid is predicted to increase the effects of doxapram. Manufacturer advises caution. Severity of interaction: Moderate Evidence for.